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The importance of the biotech and pharmaceutical industries to our economy is indisputable. Even more important than the dollars and cents, are the life-saving medicines these companies are developing. Continued investment in drug development depends on a strong and clear patent regime. The House of Representatives recently expressed its support for clarity in our patent laws, passing a reform bill that would clarify the procedure for filing certain patent term extension applications with the Patent and Trademark Office.
A provision of the Hatch-Waxman Act, passed in 1984, allows for the extension of a patent term to make up for marketing time lost during the often-lengthy process of obtaining FDA approval for a new drug or medical device. Given the enormous costs of developing new drugs, this type of patent term extension is critical to continued investment in drug research and development. During my 14 years on the House Judiciary Committee, I repeatedly heard that if drug developers lose a portion of the patent protection to which they are entitled, they will need to cut back on the amount of research they are able to conduct and, as a result, will bring fewer drugs to market.
For the Hatch-Waxman system to work, drug developers and investors must be able rely on these extensions. However, there have been inconsistent and confusing interpretations of this extension provision. Recently, a federal judge concluded that the Patent and Trademark Office and the FDA were interpreting the statute inconsistently, resulting in confusion regarding how to calculate the due date for these extensions. The court held that the Patent and Trademark Office had acted arbitrarily in rejecting an application for extension by a New Jersey pharmaceutical company -- The Medicines Company -- that makes an important anti-clotting medicine currently used to treat patients undergoing coronary angioplasty procedures.
The recently-passed House reform bill would eliminate this confusion by clarifying the way in which the extension due date should be calculated. The bill interprets the provision the same way it was interpreted by the federal judge in the recent case.
The Medicines Company invested hundreds of millions of dollars on the development of its synthetic anti-clotting drug. This drug has already been used by millions of patients undergoing coronary angioplasty procedures and has the potential to save countless more lives if important additional research is conducted. But this research, which could lead to the treatment of additional diseases, including heart attacks, strokes and peripheral artery disease, has been stalled due to uncertainty about whether the company will actually receive the patent term extension to which it is entitled under the Hatch-Waxman Act.
If passed, the reform bill would provide drug developers and investors with needed certainty, by simply making clear that the recent court decision correctly states the law for all applicants. Many patent holders could benefit from this clarification and thousands of lives could be saved. In just the last month, two other companies have asked the Patent and Trademark Office to apply the same interpretation of the extension due date calculation that the reform bill, if approved, would confirm.
As patent reform moves to the Senate for final passage, the Senate should keep in mind the importance of this provision and make sure it remains part of the final legislation.
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Source: http://www.huffingtonpost.com/william-d-delahunt/patent-reform-that-will-s_b_910687.html
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Making your home more energy efficient is multi-faceted and best done with some professional assistance or periodic advice. It is a worthy home renovation project that implies some time and effort, but it will be well worth it. There are certainly steps you can take on your own to make your home or office more energy efficient. However, some steps will necessitate a specialist.
Home renovation often means taking steps to make your home more energy efficient. In other words, it is about home improvement and giving you lower energy bills. It also is good for the environment when you use less energy. In the end, everyone wins when you take the time to enact a home improvement project focusing on your energy usage. ?
Add extra insulation to your attic and walls. When the walls and attic are well insulated, less warm or cool air escapes during the winters and summers respectively. Heat rises and therefore often escapes through an attic that lacks good insulation. You can also blow insulation into your walls in order to keep warm and cool air trapped in your home. If your walls have cavities within the studs, then blowing insulation into the walls is an option. The key here is to properly install the insulation to maximize the energy efficiency. A specialist or contractor will be able to mix and match different types of insulation in particular areas to make your home the most efficient possible.
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Provide shade to your home?s exterior with the use of trees and bushes. Place the trees and bushes in the west and east side to block sun and wind during the summers and winters respectively. This can work hand in hand with insulation measures taken. This home improvement method will also have the effect of improving your home?s aesthetic look.
Upgrade your windows. You can upgrade them or replace them altogether. Weather stripping or storm windows will make them more efficient. It is likely not very cost effective to replace windows so be sure to equip your home with energy efficient windows upon construction and focus on upgrading methods once it?s already built.
Turn your attention to your hot water system and make it more efficient. Insulate the hot water lines to trap the heat. Next, turn down your heater to the warm setting, which is still hot enough to give you the warmth you want. The setting is about 120 degrees. 3
Check out tax incentives available to make your home more energy efficient. Continue your home improvement projects with the help of tax incentives. Home renovation and improvement can be expensive. The Government has offered certain incentives to those who decide to make their home more energy efficient. Check those out and consider implementing them.
These are just five suggestions. There are a handful of other suggestions, ranging from having someone come to your home to provide a professional audit to simply changing out your light bulbs to more efficient ones. Each little step helps, adding to the overall effect of your home improvement project; making your home more energy efficient.
Make your next home improvement project one that gives you energy efficient heating and cooling by upgrading or replacing your current HVAC system. In order to make your home even more energy efficient, check out replacement windows deals and consider giving your home new windows that will greatly reduce energy costs.
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Let?s take a breather from Barack Obama?s failure to lead on the debt crisis to his failed signature policy of ObamaCare.? Despite his promise that passage of the health-insurance overhaul bill would allow people to keep their current health insurance, a new report from the National Federation of Independent Business shows that one in eight small businesses have had to stop offering insurance to their employees.? The Daily Caller notes that the change has not been voluntary:
Among the most striking of NFIB?s findings was the number of employer health insurance plans that have been or will be eliminated since PPACA?s passage ? 14 percent, or one in eight. Eliminating employer health care plans ?is the first major consequence of?PPACA that small-business owners likely feel,? the report said.
?We are not aware of any data suggesting we?ve had turnover anywhere near this level in the past,? said?William J. Dennis, a senior research fellow at the National Federation for Independent Business.
The NFIB study also found 20 percent of small employers expect to significantly change their benefit packages the next time they renew their health?insurance?plans. Almost all of them expected to see diminished benefits, increased employee costs, or both.
The report makes clear that the change has mainly been imposed on small businesses.? Left on their own, they would have continued coverage, but in response to ObamaCare, insurers have curtailed the plans offered to smaller employers:
The considerable changes expected are in part prodded by plans that have effectively been eliminated by insurers.? One of the great ?promises? of PPACA supporters was that insured people would be able to keep their current health insurance plan. As a practical matter that has not been true for a substantial number of small employers and their employees. Since enactment, one in eight (12%) small employers have either had their health insurance plans terminated or been told that their plan would not be available in the future (Q. 5).
There are some legitimate questions about this survey.? Many of the questions asked are of opinions and projections rather than already-known events.? The sample size is light as well, with only 750 businesses surveyed by NFIB.? That?s not an inadequate sample for a national survey, but it?s not exactly robust either.
Still, the core question involves events that have already transpired, which is either cancellations or notices of cancellations from insurers.? If 14 12% of the sample reported those outcomes, that means that 90 businesses have been either cut off or warned of cutoffs on their existing plans, with an impact averaging somewhere around 4500 employees.? That?s a significant result, especially given the ?you can keep your health-care plan? rhetoric coming from the White House while urging passage of ObamaCare.
It also demonstrates one reason why businesses aren?t enthusiastic about expansion.? Under these circumstances, businesses can?t price the costs of their existing staffs, let alone additions to them through capital investment and expansion.? When risk can?t be quantified with some degree of certainty, then risk simply isn?t taken ? and we get the stagnation we?ve seen for the last two years.
Update: The percentage should have been 12% (one in eight), not 14% (one in seven).? I?ve corrected the calculations as well; thanks to Ed R for the correction.
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Video Marketing
Discover how to become successul online with these effective and powerful video marketing tips
With cash being tight for lots of households, people are trying to discoverlook for ways to generate extra money and many folks are turning to the Internet. People are flocking to the Internet without knowing how much work they have to commit. It is not as easy as most people think. The truth is that for the most part, it requires hard work and you will have to invest time in order to be successful online. You have to decide if running an Internet business is the perfect option for you. The truth is that you should invest time and a great deal of energy to just get up and running, and it could take time before any money is earned. Much like any business, you take out what you invest. If time is tight because of your current occupation or family obligations and you can?t spare a couple hours daily to invest, this will not work out for you. For folks who understand that it will involve work and are ready to put in the time, putting up your own online business could be very advantageous. Below we will cover a couple of things you will need to get going.
Learn and understand what is video marketing
One thing that really is a must for long term success is for you to set up your own blog or web site. Even though it is doable to generate money online without your own site, it will be easier both starting off and in the long run. If you put up your own site, you will have the ability to establish your reputation and the reputation of your product. When you have your own web site or blog, the next thing you will need is a way to earn money from it. Most people start off with Adsense as a means to earn money from their site. If you genuinely want to earn big money with Adsense, you will have to figure out how to get hundreds or thousands of visitors to your web site daily. Of course, don?t forget about affiliate marketing, it should be one of the cornerstones of your Internet business. There is great amounts of money to be earned as an affiliate marketer if you only give it a chance. Wouldn?t it be nice to close a sale from a banner on your web site or blog and be paid $50 or more and not have to do anything for it? Clickbank is a terrific place to get going with affiliate marketing. If you truly wish to be successful, you will have to find ways to get people to check out your web site. Website traffic is the key to earning money on the Internet. Without web site traffic, don?t expect success. Many people start off turning to pay per click for obtaining traffic to their web sites. When you utilize pay per click methods, you have to pay to get people to your site, whether they purchase anything or not. Essentially, you are paying each time somebody visits your site by clicking on one of your PPC ads. If you are launching your business on a budget like almost all people do, you won?t be able to afford using PPC. But for those of you on a budget, there are no-fee traffic exchange programs. You may not think so, but there are loads of these types of no-fee traffic exchanges all over the Internet You can even perform a search on any search engine for ?free website traffic? and you will be able to locate numerous programs to help you get started. As long as you know that this is not a set and forget type of thing and that work is involved, making the extra money that you need can be accomplished by working online with your own Internet business.
Start making money online through video marketing
Tags: video marketing, video marketing tips, what is video marketing
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Flexoplex helps you to target the basis of your joint pain without making use of any pharaceutical medication. No matter whether your joint pain can be caused by arthritis or it?s only as a result of damage of everyday life. When your joint pain and tenderness be a serious issue you will need to deal with it.
This soreness in joints and also arthritis is due to the wearing away, swelling, as well as inadequate lubrication of joints. But most of these issues can be treated and also prevented. The merchandise which will provide relief for all your major reasons of joint and arthritic pain is Flexoplex. It is a natural product that is very effective.
This remedy will be able to provide long-lasting pain relief as a result of specialized and powerful ingredients its full of.The FlexoPlex review information how Glucosamine, MSM as well as Chondroitin work in order to bring back along with repair the eroded and damaged joints. Joints are lubricated from the essential fatty acids as well as soothed by the natural Cox-2 inhibitors which are comprised in Flexoplex.
It is possible to relish increased range of motion besides better moisturized joints besides enhanced mobility and also better flexibility. All this will probably be together with reduced pain. In addition, It likewise helps to boost bone health, as well as boost the flow of blood and beneficial nutrients to tissues and also cartilage. Besides it can help to encourage the synthesis of synovial fluid apart from the cartilage matrix. But the production of the powerful painkillers that is generated by the body, the endorphins and enkephalins, does not get affected.
In actual fact, it tends to provide the most sensible and multi-level approach to be able to tackle joint pain. Another supplements will not be able to offer getting rid of the major factors behind joint or arthritis pain, given that they is missing many of the key things that are found only in this supplements.
Looking to find the best deal on Flexoplex, then visit Sophie Addison websites to find the best advice on Best Flexoplex Joint Relief for you.
Source: http://articlesobserver.com/health-fitness/rediscover-a-pain-free-life-with-flexoplex
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As humans any kind of decoration and beautification of our surroundings comes naturally to us as we have that special sense of appreciation which distinguishes us. Since we have moved away from our basic surroundings and have taken up a rather industrialized take on life therefore it is extremely important that we stay in touch with the green spot through our garden spaces which not only comprise of herbs, shrubs, trees and plants but also of many other intricate components like garden arbors and pergolas which highly accentuate the space. Adding an arbor to your garden is a quick and easy way to create a focal point within the space and boost your home?s curb appeal. Arbors are highly customizable, with designs ranging from those that rise up over a gate in a fence, to others that can be built with a bench seat underneath, creating a quiet nook for reading and relaxing in the garden. If you?ve decided to build or purchase an arbor for your yard, one of the most important decisions you?ll need to make is the type of material.
Garden arbors are easily available in a wide range and variety which includes the wooden ones, the metal arbors and also the vinyl arbors. Wood is a very classic and natural material choice that has been around since the beginning of time. But there are some durability factors that go hay way when one wants to have wooden arbors fixed in the open spaces. Arbors today are designed from an all new material, vinyl that has the finish and beauty of wood along with the strength of metal and the resistance of plastic. Vinyl arbors are highly durable and can be easily maintained without any external efforts.
These arbors offer a unique look to the doorway, swings, gates, centerpieces and benches which add to the impeccable beauty of the place as a whole. It is completely up to the buyer that he chooses a wooden arbor for sweet aroma of jasmine or Italian vinyl pergolas style for producing grapes. We may not have grand homes, but we can certainly have lovely gardens accented with an arbor or two. An arbor enhances the beauty of any private area around a home and invites one to spend time in a peaceful setting out of doors for meditation and reflection. Choosing upon the kind of arbor one would like to install is personally ones own choice however picking the medium on which the entire structure is formulated stands utmost important as it spells the value of your investment.
Source: http://www.mrimbhu.com/?p=1918
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